Abstract
Fatigue is common and usually resolves with rest. If it persists despite adequate recovery, it may indicate myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS), characterized by profound asthenia with somatic and neurocognitive disturbances. Often underdiagnosed, it can be triggered by infections, stress, psychiatric disorders, vitamin deficiencies, endocrine dysfunctions, or surgical procedures. This case report describes a patient affected after a severe infection.